BioMed Research International / 2014 / Article / Fig 3

Research Article

Microarray-Based RNA Profiling of Breast Cancer: Batch Effect Removal Improves Cross-Platform Consistency

Figure 3

Correlation and ICC analysis. Box plots illustrating the pair-wise sample-sample correlation coefficients when no adjustment was applied and after intraplatform adjustment for batch effects using ComBat for all 243 sample pairs using the 18424 shared genes (a) and pair-wise gene-gene correlation coefficients for all 18424 gene-pairs across all 243 samples (b). Box plots illustrating effects of intraplatform, between-platform adjustment, and high-variance genes on the pair-wise gene-gene ICC coefficient measured for all 18424 gene-pairs across all 243 samples (c).
651751.fig.003a
(a)
651751.fig.003b
(b)
651751.fig.003c
(c)

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.