Figure 5: Mice paw edema induced by different doses of CoaPLA2. Positive control was the total venom of Crotalus Oreganus Abyssus and negative control was DMSO/PBS solution. Edema was expressed as the percentage increase in the paw volume of the treated group, compared to that of the control group at each time interval. Edema-inducing percentage is expressed as the mean ± SD of three independent experiments performed in triplicate ( ).