In Vitro Antiviral Activity of Circular Triple Helix Forming Oligonucleotide RNA towards Feline Infectious Peritonitis Virus Replication

Figure 1

Denaturing PAGE to determine circular TFO RNA. Denaturing PAGE analysis confirmed that linear TFOs were successfully circularized, whereas circular TFOs migrated faster than linear TFOs; however, only slight variation was detected for some of the TFOs. O1 to O7 represent linear TFO1 to TFO7, while Cir1 to Cir7 represent circular TFO1 to TFO7.