Age-Related Alterations in Endothelial Function of Femoral Artery in Young SHR and WKY Rats

<table>Vascular constrictions induced by noradrenaline (NA, 10 <i>μ</i>mol/L) in the femoral artery of young adult (22-week-old) and juvenile (7-week-old) Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR). SHR-7: 7-week-old SHR; SHR-22: 22-week-old SHR; WKY-7: 7-week-old WKY rats; WKY-22: 22-week-old WKY rats. Values represent mean ± SEM of 6–8 rats. Symbols have the following meanings: <svg height="13.6875" id="M30" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 64.949997 13.6875" width="64.949997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared to age-matched WKY (SHR-7 versus WKY-7, SHR-22 versus WKY-22), <svg height="13.95" id="M31" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 66.324997 13.95" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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q0 -76 10 -138.5t37 -107.5t69 -45q32 0 55.5 25t35.5 68.5t17.5 91.5t5.5 105t-5.5 105.5t-18 92t-36 68t-56.5 24.5z" id="x30"></path></g><g transform="matrix(.017,-0,0,-.017,58.093,13.688)"><path d="M153 550l-26 -186q79 31 111 31q90 0 141.5 -51t51.5 -119q0 -93 -89 -166q-85 -69 -173 -71q-32 0 -61.5 11.5t-41.5 23.5q-18 17 -17 34q2 16 22 33q14 9 26 -1q61 -50 124 -50q60 0 93 43.5t33 104.5q0 69 -41.5 110t-121.5 41q-53 0 -102 -20l38 305h286l6 -8
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</svg> compared to juvenile rats (WKY-22 versus WKY-7, SHR-22 versus SHR-7).</table>

BioMed Research International

fig6

Figure 6

Figure 6: Age-Related Alterations in Endothelial Function of Femoral Artery in Young SHR and WKY Rats 