Research Article

A Comparative Performance Analysis of Total PSA, Percentage Free PSA, PSA Velocity, and PSA Density versus the Detection of Primary Circulating Prostate Cells in Predicting Initial Prostate Biopsy Findings in Chilean Men

Table 5

Number of possible avoided biopsies and missed cancers according to the parameter used to determine the need for a prostate biopsy.

Avoided biopsiesMissed cancers
(% of total cancer)
cancer/total population

% free PSA >15%161 (53.1%)33 (29.2%)113/303
PSA velocity <0.75 ng/mL/year161 (53.1%)46 (40.7%)113/303
PSA density <0.15 ng/mL 174 (57.%)44 (38.9%)113/303
CPC negative181 (59.7%) 13 (11.5%)113/303