BioMed Research International / 2014 / Article / Tab 1

Clinical Study

Microbleeds in Late-Life Depression: Comparison of Early- and Late-Onset Depression

Table 1

Demographic, neuropsychosocial, and radiological characteristics of all subjects.

Control
( )
EOD
( )

(versus control)
POD
( )

(versus control)
LOD
( )

(versus control)

Age, years 0.669 0.422 0.236
Female41 (48.2%)37 (64.9%)0.05035 (64.8%)0.05653 (63.1%)0.052
Education, years 0.956 0.238 0.645
Hypertension52 (61.2%)37 (64.9%)0.65233 (61.1%)0.99459 (70.2%)0.215
Diabetes24 (28.2%)12 (21.1%)0.33516 (29.6%)0.86029 (34.5%)0.378
MMSE 0.522 0.038 0.002
LSNS 0.000 0.001 0.050
SLE 0.000 0.000 0.511
GDS 0.000 0.000 0.000
Grade of PWMH 0.214 0.038 0.000
Grade of DWMH 0.441 0.182 0.000
Prevalence of SBI28 (32.9%)17 (29.8%)0.69625 (46.3%)0.11447 (56.0%)0.003
Prevalence of microbleeds in
 Any region20 (23.5%)13 (22.8%)0.92015 (27.8%)0.57435 (41.7%)0.012
 Left hemisphere10 (11.8%)7 (12.3%)0.92612 (22.2%)0.10028 (33.3%)0.001
 Right hemisphere14 (16.5%)10 (17.5%)0.7218 (14.8%)0.79420 (23.8)0.234
 Infratentorial9 (10.6%)5 (8.8%)0.7227 (13.0%)0.66913 (15.5%)0.345
 Lobar10 (11.8%)8 (14.0%)0.69011 (20.4%)0.16727 (32.1%)0.001
 Deep14 (16.5%)11 (19.3%)0.6659 (16.7%)0.97622 (26.2%)0.123

EOD: early-onset depression; POD: presenile-onset depression; LOD: late-onset depression; MMSE: minimental state examination; LSNS: Lubben Social Network Scale; SLE: Scale of Life Events; GDS: Geriatric Depression Scale; PWMH: periventricular white matter hyperintensities; DWMH: deep white matter hyperintensities; SBI: silent brain infarction.

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