Formulation Optimization of Erythromycin Solid Lipid Nanocarrier Using Response Surface Methodology

Table 2

The effect of surfactant (Poloxamer 188) concentration (%w/v) on mean particle size, %EE, and %DL of ERY-SLNs.

Lipid	Poloxamer 188; concentration (%w/v)	Mean particle; size (nm)	EE (%)	DL (%)
GMS	1	337.96±9.81	79.99±4.89	25.99±1.63
	2	138.42±17.48	84.52±5.58	28.17±1.86
	3	224.29±11.69	79.14±3.69	26.37±1.23
	4	338.76±9.51	68.42±5.06	22.80±1.68
	5	387.29±9.15	67.47±5.60	22.48±1.86