BioMed Research International

Review Article

Alternative Splicing Generates Different Parkin Protein Isoforms: Evidences in Human, Rat, and Mouse Brain

Table 5

List of antibodies targeting PARK2 isoforms.


Antibody group #	Generic name		Target domain
	Trade name	Companies

#1	H00005071-B01P	Abnova	1 aa–387 aa
	H00005071-D01P	Abnova
	H00005071-D01	Abnova

#2	OASA06385	Aviva System biology	83 aa–97 aa
	AHP495	AbD Serotec
	MD-19-0144	Raybiotech, Inc.
	DS-PB-01562	Raybiotech, Inc.
	PAB14022	Abnova

#3	MCA3315Z	AbD Serotec	288 aa–388 aa
	H00005071-M01	Abnova

#4	PAB1105	Abnova	62 aa–80 aa
	70R-PR059	Fitzgerald

#5	PAB0714	Abnova	305 aa–323 aa
	AB5112	Millipore Chemicon
	R-113-100	Novus biologicals

#6	P5748	Sigma	298 aa–313 aa
	GTX25667 Parkin antibody CR20121213_GTX25667	GeneTex International Corporation
	ABIN122870	Antibodies on-line
	PA1-751	Thermo Fisher Scientific, Inc.

#7	R-114-100	Novus biologicals	295 aa–311 aa
	Anti-Parkin, aa295-311 h Parkin; C-terminal	Millipore Chemicon

#8	MAB5512	Millipore Chemicon	399 aa–465 aa
	Anti-Parkin antibody, clone PRK8/05882	Millipore Upstate
	Parkin (PRK8): sc-32282	Santa Cruz

#9	Parkin (H-300): sc-30130	Santa Cruz	61 aa–360 aa
	Parkin (D-1): sc-133167	Santa Cruz
	Parkin (H-8): sc-136989	Santa Cruz

#10	EB07439	Everest Biotech	394 aa–409 aa
	GTX89242 PARK2 antibody, internal CR20121213_GTX89242	GeneTex International Corporation
	NB100-53798	Novus biologicals

#11	GTX113239 Parkin antibody [N1C1] CR20121213_GTX113239	GeneTex International Corporation	28 aa–258 aa

#12	10R-3061	Fitzgerald	390 aa–406 aa

#13	A01250-40	GenScript	300 aa–350 aa

#14	NB600-1540	Novus biologicals	399 aa–412 aa

#15	ARP43038_P050	Aviva System biology	311 aa–360 aa

Antibodies against canonical PARK2 isoform (NP_004553.2) were grouped if they recognize the same epitope. To each group was assigned a new identification code (#).