Amelioration of LPS-Induced Inflammation Response in Microglia by AMPK Activation
Figure 3
ENERGI-F704 reduced LPS-induced IL-6 and TNF-α secretion in BV2 cells. BV2 cells were incubated with 200 ng/mL LPS in the presence of ENERGI-F704 or AICAR for 24 h. The levels of IL-6 (a) and TNF-α (b) in culture medium of each condition were accessed using ELISA analysis. Data are presented as the mean ± SEM of three independent experiments (one-way ANOVA; , ; specific comparison to LPS-treated control).