Comparison of Proton Pump Inhibitor and Histamine-2 Receptor Antagonist in the Prevention of Recurrent Peptic Ulcers/Erosions in Long-Term Low-Dose Aspirin Users: A Retrospective Cohort Study

Table 1

Demographic data of patients taking long-term low-dose aspirin.

Variables	Famotidine group ()	Omeprazole group ()	value
Age (year)	74.4 ± 10.5	73.3 ± 10.6	0.6
≥60 years old	44 (89.8%)	48 (87.3%)	0.7
Male gender	42 (85.7%)	42 (76.4%)	0.2
Time to follow-up EGD* (weeks)	25.0 ± 2.3	24.5 ± 2.1	0.2
Smoking	6 (12.2%)	8 (14.5%)	0.7
Alcohol consumption	2 (4.1%)	3 (5.5%)	1.0
Coffee consumption	4 (8.2%)	7 (12.7%)	0.4
Tea consumption	15 (28.6%)	8 (14.5%)	0.8
Cirrhosis	1 (2.0%)	1 (1.8%)	1.0
Hiatus hernia	18 (36.7%)	18 (32.7%)	0.7
History of upper GIB^†	10 (20.4%)	12 (21.8%)	0.9
History of erosive esophagitis	8 (16.3%)	17 (30.1%)	0.08
History of H. infection	19 (38.8%)	14 (25.5%)	0.1
Concomitant medication
Steroids	3 (6.1%)	2 (3.6%)	0.6
Short-term NSAID^‡	5 (10.2%)	7 (12.7%)	0.7

*EGD: esophagogastroduodenoscopy.
^†GIB: upper gastrointestinal bleeding.
^‡NSAID: nonsteroidal anti-inflammatory drug.