Research Article

Comparison of Proton Pump Inhibitor and Histamine-2 Receptor Antagonist in the Prevention of Recurrent Peptic Ulcers/Erosions in Long-Term Low-Dose Aspirin Users: A Retrospective Cohort Study

Table 3

Follow-up endoscopic findings of patients taking long-term low-dose aspirin.

Famotidine group ()Omeprazole group () value

Lanza scale1.7 ± 1.11.2 ± 0.70.008
Gastroduodenal ulcer/erosion*15 (30.6%)5 (9.1%)0.005
 Ulcer10 (20.4%)3 (5.5%)0.04
  Gastric ulcer62
  Duodenal ulcer31
  Gastric ulcer & duodenal ulcer10
 Erosion5 (10.2%)2 (3.6%)0.2
  Gastric erosion51
  Gastric erosion & duodenal erosion01
Erosive esophagitis7 (14.3%)7 (12.7%)1.0

*Results were presented as the most severe mucosal injury found on endoscopy.
One patient in famotidine group had gastric ulcer bleeding.