Induction of Apoptosis in Human Multiple Myeloma Cell Lines by Ebselen via Enhancing the Endogenous Reactive Oxygen Species Production

Figure 2

Ebselen induced apoptosis of MM cells analyzed by FACS, stained with annexin V-FITC/PI. (a) and (b) display the results of the cells treated with ebselen in a concentration and time dependent manner, respectively. The data is also showed in histogram (c). Data are presented as mean ± SD (𝑛=3). *Significant difference compared to the control group (^∗𝑃<0.05, ^∗∗𝑃<0.01, one-way ANOVA with Scheffe’s test).

(a)

(b)

(c)