BioMed Research International / 2014 / Article / Fig 3

Review Article

Aptamers as Both Drugs and Drug-Carriers

Figure 3

Reduction in size of the RNA sequence space for experimental screening and selection of RNA aptamers by in silico approach. The secondary structure of more than RNA sequences was analyzed to select 105 sequences for the RNA 3D structure library. The high-throughput virtual screening of the developed library selected 103-104 sequences suitable for the experimental screening and verification.