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Figure 1: EGF and neuregulin-1 (NGR1) in body fluids mediate eyelid opening. The picture depicts the acceleration of eyelid opening following subcutaneous injections of EGF into pups. EGF (1.0 mg/kg) was subcutaneously injected to rat neonates daily from postnatal day 2 to postnatal day 10. The table shows that both EGF and NGR1 are detected in human body fluids including saliva, serum, urine, and amniotic fluids. ND: not determined.