Caffeic Acid Phenethyl Ester Protects against Amphotericin B Induced Nephrotoxicity in Rat Model

Table 2

BUN and serum creatinine levels in rats subjected to amphotericin induced nephrotoxicity.

GROUPS	𝑛	BUN (mg/dL)	Creatinine (mg/dL)
1-Control	10	21.4 ± 3.4	0.58 ± 0.10
2-CAPE	9	18.7 ± 2.6	0.51 ± 0.03
3-AmB	7	73.5 ± 39.2	1.61 ± 1.13
4-AmB + CAPE	7	88.5 ± 29.1	1.54 ± 0.74
𝑃-values
1-2		NS	NS
1–3		<0.0001	<0.0001
1–4		<0.0001	=0.005
2-3		<0.0001	<0.0001
2–4		<0.0001	=0.003
3-4		NS	NS

NS: not significant. Values are expressed as mean ± standard error of mean.