Research Article

Intracerebroventricular Administration of Nerve Growth Factor Induces Gliogenesis in Sensory Ganglia, Dorsal Root, and within the Dorsal Root Entry Zone

Figure 4

Phenotypic analysis of the proliferating cells within the sensory ganglia. The asterisk marks the perikaryon of a sensory neuron within the neuronal soma compartment (Ne). BrdU positive nuclei, here marked by black arrows, surround the perikaryon. On the lower left side, the axonal compartment (Ax) of the DRG is depicted. Black arrowheads point at elongated BrdU positive nuclei, which are oriented in parallel to axons (a). Scale bar = 50 μm. BrdU positive nuclei (red) are associated with the Schwann and satellite cell marker S100β (green) and do not colocalize with NeuN (blue), a marker for neuronal nuclei (b). Scale bar = 20 μm.
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(a)
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(b)