Research Article

A Derived Network-Based Interferon-Related Signature of Human Macrophages Responding to Mycobacterium tuberculosis

Table 10

GSEA using transcriptome data of PBMCs from human patients with other inflammatory or pathological conditions.

Group comparison1THP1r2Mtb-inducedTMtb-iNetTMtb-iEx
NES2FDR3Correlation3NES2FDR3Correlation3NES2FDR3Correlation3

Type I diabetes versus HC−1.34 0.112 Null−1.21 0.329 Null−1.13 0.336 Null
Staph versus HC−1.09 0.305 Null−1.29 0.334 Null1.00 0.441 Null
Liver-transplant versus HC−0.79 0.892 Null−0.92 1.000 Null0.90 0.647 Null
E.  coli versus HC−0.91 0.646 Null−1.02 1.000 Null1.20 0.156 Null
Melanoma versus HC−0.91 0.641 Null−0.92 1.000 Null0.92 0.622 Null
SLE versus HC−1.14 0.396 Null−1.22 0.540 Null−1.04 0.490 Null
JIA versus HC−0.74 1.000 Null−0.76 1.000 Null−0.73 0.908 Null

1Staph: Staphylococcus aureus infection; liver-transplant: liver-transplant undergoing immunosuppressive therapy; melanoma: metastatic melanoma; SLE: systemic lupus erythematosus; JIA: systemic juvenile idiopathic arthritis.
2,3The same as Table 1.