C-Kit Expression, Angiogenesis, and Grading in Canine Mast Cell Tumour: A Unique Model to Study C-Kit Driven Human Malignancies
Figure 2
(a) Poorly differentiated G3 CMCT with high MVD. Double staining is performed combining immunohistochemistry with toluidine blue histochemistry. Many scattered degranulated blue stained mast cells. Single arrows indicate red-brown immunostained microvessels with primary anti-FVIII-RA. Note as an internal positive control the red blood cell in the lumen of microvessel. ×1000 in oil magnification. (b) Well-differentiated G1 CMCT with low MVD. Double staining is performed combining immunohistochemistry with toluidine blue histochemistry. Many scattered granulated red-blue stained mast cells. Single arrows indicate red immunostained microvessels with primary anti-FVIII-RA. Note as an internal positive control the red blood cell in the lumen of microvessel. ×1000 in oil magnification.
