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BioMed Research International
Volume 2014, Article ID 734281, 9 pages
Review Article

Treatment of Malignant Gliomas in Elderly Patients: A Concise Overview of the Literature

Medical Oncology 1 Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy

Received 14 February 2014; Accepted 20 March 2014; Published 22 April 2014

Academic Editor: Anna Luisa Di Stefano

Copyright © 2014 Patrizia Farina et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Gliomas are the most frequent primary brain tumors and the incidence data has increased in the elderly population. Unfortunately, prospective studies on this population are few and so the right treatment is unknown. In the elderly patients no standard treatment has been established and therefore the optimal treatment should be individualized. We performed a review analyzing the prognostic and predictive factors, the clinical studies, and the correct management of this population.