Investigation of the Interaction between Patulin and Human Serum Albumin by a Spectroscopic Method, Atomic Force Microscopy, and Molecular Modeling

Table 3

Secondary structure determination for free HSA and its drug complexes in Trisbuffer (pH = 7.4) at different molar concentration ratios for HSA and patulin.

Molar ratio (patulin-HSA)	𝛼-helical (%)	𝛽-sheet (%)	𝛽-turn (%)	Random coil (%)
0 : 1	55.3	8.7	15.3	20.7
1 : 1	52.7	9.1	15.6	22.6
2 : 1	50.7	10.6	17.4	21.3