Chemical Composition, Leishmanicidal and Cytotoxic Activities of the Essential Oils from Mangifera indica L. var. Rosa and Espada

Table 2

Leishmanicidal and cytotoxic effects of essentials oils of M. indica L.

Treatment	Promastigote IC50 (𝜇g/mL)	Macrophage CC50 (𝜇g/mL)	Selectivity index
EOMiR	39.1±5.6	142.8±6.0	3.7
EOMiE	23.0±2.7	158.6±2.5	6.9

The leishmanicidal activity was expressed as the IC₅₀ and CC₅₀ by the linear regression analysis, respectively. Values are mean ± standard deviation from at least three independent experiments in duplicate. Differences were considered significant at a 0.05 level of confidence. SI: CC₅₀ macrophages/IC₅₀ promastigote forms. IC₅₀: concentration inhibiting 50% of the growth of promastigotes; CC₅₀: concentration capable of causing cytotoxic effects of macrophages by 50%.