735292.fig.003a
(a)
735292.fig.003b
(b)
Figure 3: Methylation pattern of promoter CpG-island of CTDSPL gene in ccRCC. Bisulfite sequencing data for ccRCC sample number 8 from Figures 1 and 2 is represented. Twenty-four CpG-dinucleotides (a) are shown in grey. Primers for bisulfite sequencing (a) are marked in italic. NotI-site is underlined (a). In table (b) methylated (grey squares) and unmethylated (white squares) CpG-dinucleotides are shown for 7 sequenced clones. CpG-dinucleotides that correspond to NotI-site are marked in bold and underlined.