Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014, Article ID 737109, 7 pages
http://dx.doi.org/10.1155/2014/737109
Clinical Study

Peri- and Postanalgesic Properties of Lidokain, Lornoxicam, and Nitroglycerine Combination at Intravenous Regional Anesthesia

1Anesthesiology and Reanimation Department, Baskent University School of Medicine, Baskent University, Alanya Hospital, Saray Mah, Kızlarpınarı Caddesi No. 1, 07400 Alanya, Antalya, Turkey
2Orthopedics and Traumatology Department, Baskent University School of Medicine, Baskent University, Alanya Hospital, Saray Mah, Kızlarpınarı Caddesi No. 1, 07400 Alanya, Antalya, Turkey
3Anesthesiology and Reanimation Department, Baskent University School of Medicine, Baskent University, Ankara Hospital, Fevzi Çakmak Caddesi No. 10 Sokak No. 45, Bahçelievler, 06490 Ankara, Turkey

Received 14 December 2013; Accepted 30 January 2014; Published 9 March 2014

Academic Editor: Ahmet Eroglu

Copyright © 2014 Biricik Melis Cakmak et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. This study was conducted to compare and evaluate the effect of adding lornoxicam or nitroglycerine as adjuncts to lidocaine in intravenous regional anesthesia (IVRA). Methods. 60 patients were randomly separated into three groups, lidocaine group (group L), lidocaine + lornoxicam group (group LL), and lidocaine + lornoxicam + transdermal nitroglycerine group (group LL-N). Hemodynamic parameters, sensory and motor blocks onset, and recovery times were recorded. Analgesic consumption for tourniquet pain and postoperative period were recorded. Results. Sensory block onset times and motor block onset times were shorter in the LL-N and LL groups compared with L group. Sensory block recovery time and motor block recovery time were prolonged in the LL and LL-N groups compared with group L. The amount of fentanyl required for tourniquet pain was less in group LL and group LL-N when compared with group L. VAS scores of tourniquet pain were higher in group L compared with the other study groups. Postoperative VAS scores were higher for the first 4 hours in group L compared with the other study groups. Conclusion. The adjuvant drugs (lornoxicam or TNG) when added to lidocaine in IVRA were effective in improving the overall quality of anesthesia, reducing tourniquet pain, increasing tourniquet tolerance, and improving the postoperative analgesia.