Synthesis and Antihypertensive Screening of New Derivatives of Quinazolines Linked with Isoxazole

<table>Chemical structure of active chemotherapeutic antihypertensive agents (prazosin, terazosin, and doxazosin) and rationally designed template for targeted compound (<b>24</b>). RSBP (rise in systolic blood pressure), RMAP (rise in mean atrial blood pressure).</table>

BioMed Research International

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Figure 1

Figure 1: Synthesis and Antihypertensive Screening of New Derivatives of Quinazolines Linked with Isoxazole 