Ibuprofen Protects Ventilator-Induced Lung Injury by Downregulating Rho-Kinase Activity in Rats

Figure 6

Representative lung histology in the control, HVZP, HVZP + ibuprofen (Ibu) 15 mg/kg, and HVZP + ibuprofen 30 mg/kg groups. The treatment details are given in the legend of Figure 1. Control group showing no major histologic abnormalities. HVZP group showing patchy areas of hemorrhage and thickened alveolar walls with inflammatory cells infiltration. HVZP + Ibu 15 mg/kg and HVZP + Ibu 30 mg/kg groups showing less hemorrhage and mild inflammatory cell infiltration.