Ibuprofen Protects Ventilator-Induced Lung Injury by Downregulating Rho-Kinase Activity in Rats
Figure 7
Representative electron micrographs of the control, HVZP, HVZP + ibuprofen (Ibu) 15 mg/kg, and HVZP + ibuprofen 30 mg/kg groups. The capillary profile was normal and is lined by continuous endothelium (black arrow). The HVZP group showed discontinuous endothelial cell lining (white arrow) and large endothelial cell membrane vacuolization () protruding into the capillary lumen. The ultrastructure of the HVZP + Ibu 15 mg/kg and HVZP + Ibu 30 mg/kg groups revealed normal endothelial continuity as the control group. EC: erythrocyte, EN: endothelium, and A: alveolar space.
We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.
