BioMed Research International / 2014 / Article / Fig 7

Research Article

Ibuprofen Protects Ventilator-Induced Lung Injury by Downregulating Rho-Kinase Activity in Rats

Figure 7

Representative electron micrographs of the control, HVZP, HVZP + ibuprofen (Ibu) 15 mg/kg, and HVZP + ibuprofen 30 mg/kg groups. The capillary profile was normal and is lined by continuous endothelium (black arrow). The HVZP group showed discontinuous endothelial cell lining (white arrow) and large endothelial cell membrane vacuolization ( ) protruding into the capillary lumen. The ultrastructure of the HVZP + Ibu 15 mg/kg and HVZP + Ibu 30 mg/kg groups revealed normal endothelial continuity as the control group. EC: erythrocyte, EN: endothelium, and A: alveolar space.

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