BioMed Research International / 2014 / Article / Tab 1

Research Article

Alterations of the Myovesical Plexus of the Human Overactive Detrusor

Table 1

Semiquantitative analysis of intrafascicular N-cadherin and PGP9.5 expression in control and overactive detrusor.

Fascicle 1Fascicle 2Fascicle 3Fascicle 4
N-cadPGP9.5N-cadPGP9.5N-cadPGP9.5N-cadPGP9.5

GSI1+++++++++++
+++++++++++++
2+++++++++ErrorError
+++++++++
3++++++++++
++++++++++++
4++++++++++
++++++++++++
5+++++++++++
+++++++++++

NDO1+++++++++ErrorError
+++++++++++
2++++++++++
+++++++
3+++++++++++
++++++++
4+++ErrorError++ErrorError
+++++++++
5++++++++++++
+++++++++
6++ErrorError+++++
++++++++

BDO1++++++++++
+++++++++
2++++++++++++
+++++++++++
3+++++++++ErrorError
++++++++
4++++ErrorError+++++
++++++++++
5++++++++++
++++++++++++
6++++++++++++
++++++++++++++

IDO1+++++++++++
++++++++++++
2ErrorError+++ErrorError+++
++++++++++
3++++++++++++
+++++++++
4+++++++++++ErrorError
+++++++++
5++++++ErrorError++
++++++++++++
6++++++++++++++
++++++++++++

Smooth muscle fascicles were semiquantitatively analysed for intrafascicular expression of N-cadherin and PGP9.5, and graded as follows: features not present in any photographs, − (no expression); present >0–1/3, + (low expression); present in 1/3–2/3, ++ (intermediate expression); present in 2/3–entire fascicle, +++ (high expression). BDO: DO due to bladder outlet obstruction; NDO: neurogenic DO; IDO: idiopathic DO; GSI: genuin stress incontinence = control bladder. Note the heterogeneity of N-cadherin and PGP9.5 expression profile throughout the control and overactive specimens. In some cases, fatty tissue texture complicated specimen processing. Therefore, we were unable to study some fascicles (see: error).