Review Article

Extracellular Matrix Modulates Angiogenesis in Physiological and Pathological Conditions

Figure 1

A schematic drawing of the extracellular matrix molecular organization. The interstitial matrix is mainly composed of collagen, fibronectin, elastin, and proteoglycans (a). The extracellular basement membrane mainly consists of collagen IV, laminin, entactin, and heparan sulfate proteoglycans which bind to VEGF (b).
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(a)
756078.fig.001b
(b)