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BioMed Research International
Volume 2014 (2014), Article ID 758432, 5 pages
http://dx.doi.org/10.1155/2014/758432
Clinical Study

Experience of 1166 Thyroidectomy without Use of Prophylactic Antibiotic

1Department of General Surgery, TungWah Affiliated Hospital of Sun Yat-sen University, Dongguan, Guangdong 523110, China
2Department of Surgical Oncology, Tung Wah Affiliated Hospital of Sun Yat-sen University, Dongguan, Guangdong 523110, China
3Operating Room Tung Wah, Tung Wah Affiliated Hospital of Sun Yat-sen University, Dongguan, Guangdong 523110, China

Received 4 February 2014; Revised 23 February 2014; Accepted 22 March 2014; Published 12 May 2014

Academic Editor: Roberto Cirocchi

Copyright © 2014 Qiang Lu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Although the procedure requires a small surgical incision and a short duration, incision infection rate is very low in thyroidectomy; however, doctors still have misgivings about infection events. Aim. We retrospectively analyzed the prevention of incision infection without perioperative use of antibacterial medications following thyroidectomy. Materials and Methods. 1166 patients of thyroidectomy were not administered perioperative antibiotics. Unilateral total lobectomy or partial thyroidectomy was performed in 68.0% patients with single-side nodular goiter or thyroid adenoma. Bilateral partial thyroidectomy was performed in 25.5% patients with nodular goiter or Graves’ disease. The mean time of operation was 80.6 ± 4.87 (range: 25–390) min. Results. Resuturing was performed in two patients of secondary hemorrhage from residual thyroid following bilateral partial thyroidectomy. Temporally recurrent nerve paralysis was reported following right-side total lobectomy and left-side subtotal lobectomy in a nodular goiter patient. One case had suppurative infection in neck incision 5 days after bilateral partial thyroidectomy. Conclusions. Thyroidectomy, which is a clean incision, involves a small incision, short duration, and minor hemorrhage. If the operation is performed under strict conditions of sterility and hemostasis, antibacterial medications may not be required to prevent incision infection, which reduces cost and discourages the excessive use of antibiotics.