Molecular Imaging in Stem Cell Therapy for Spinal Cord Injury
Figure 2
The time course of viability of transplanted NSPCs for SCI. (a) Images of a representative mouse that received acute transplantation (TP) of luciferase-expressing NSPCs confirmed long-term cell viability. Drastic reductions in signal intensity within the first 4 days after transplantation and then relatively stable bioluminescent signals for the following 6 wk were observed in both acute and delayed transplantation groups. There were no differences between acute and delayed transplantation groups in both value of signal intensity (b) and the rate to initial value (c) at each time point. Values are means ± SE . (d) The correlation between grafted cell numbers and luminescent intensity was confirmed in vivo. Values are means ± SE [59].
