Research Article
High-Throughput Functional Screening of Steroid Substrates with Wild-Type and Chimeric P450 Enzymes
Table 1
Alignment of amino acid sequences of the J-helix of the four parental wild-type CYP1A enzymes studied in this work.
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HS: Homo sapiens, Mm: Mus musculus, and Oc: Oryctolagus cuniculus. The solid triangles indicate the charged residue discussed in the text; a dot represents an amino acid residue identical to that of Mm CYP1A1 sequence. | ||||||||||||||