Oxidative Stress, Hypoxia, and Autophagy in the Neovascular Processes of Age-Related Macular Degeneration

Figure 4

EpiphaNet interactive map for angiogenesis, autophagy, and age-related macular degeneration (AMD) (reproduced from the EpiphaNet software for better visibility of interactions; Angpt1 and Tek are genes encoding angiopoietin-1 and its receptor, respectively; Pecam gene encodes platelet endothelial cell adhesion molecule (PECAM-1); Igf2 bp2: insulin-like growth factor 2 mRNA-binding protein 2; Khdrbs1: KH domain containing, RNA binding, signal transduction associated 1; Nup52: nucleoporin 52, component of the p62/sequestome 1 complex; Sqstm1: sequestome 1; VEGF: vascular endothelial growth factor).