Gender-Dependent Effect of GSTM1 Genotype on Childhood Asthma Associated with Prenatal Tobacco Smoke Exposure

Table 3

Association of prenatal TSE and childhood asthma in individuals of different genders and GSTM1 genotypes.

		Childhood asthma
		No TSE Asthma number/total number (percentage)	Prenatal TSE Asthma number/total number (percentage)		OR	95% CI
		OR (95% CI)	OR (95% CI)
Male	GSTM1	28/101 (27.7%)	10/33 (30.3%)	0.775	1.134	0.479–2.681
		1.000 (reference)	1.000 (reference)
Male	Null	32/129 (26.4%)	20/57 (35.1%)	0.227	1.510	0.773–2.952
		0.933 (0.519–1.676)	1.243 (0.495–3.121)
Female	GSTM1	17/88 (19.3%)	7/30 (23.3%)	0.637	1.271	0.469–3.448
		1.000 (reference)	1.000 (reference)
Female	Null	12/127 (9.4%)	12/40 (30.0%)	0.001	4.107	1.669–10.107
		0.436 (0.197–0.966)	1.408 (0.477–4.159)