Gender-Dependent Effect of GSTM1 Genotype on Childhood Asthma Associated with Prenatal Tobacco Smoke Exposure

Table 4

The GSTM1 null genotype presented a lower prevalence of house dust mite sensitization and food allergen sensitization compared with positive GSTM1 in boys and girls without prenatal TSE, but the difference was not significant.

	Male					Female
	GSTM1		Null			GSTM1		Null
6 y HDM sensitization*	51/100	51.0%	57/126	45.2%	0.389	37/87	42.5%	48/122	39.3%	0.644
6 y food allergen sensitization^#	27/100	27.0%	31/126	24.6%	0.682	22/87	25.3%	23/122	18.9%	0.265
6 y any sensitization^†	59/100	59.0%	66/126	52.4%	0.32	42/87	48.3%	52/122	42.6%	0.418

HDM sensitization is defined by a specific IgE response to house dust mites (d1) 0.35 kU/L.
^#Food allergen sensitization is defined by a detectable serum specific IgE (≥0.35 kU/L) response to one or more food allergens (egg white, cow’s milk, peanut, or shrimp).
Any sensitization is defined by a detectable serum specific IgE (≥0.35 kU/L) response to one or more common allergens (egg white, cow’s milk, peanut, shrimp, house dust mite, or German cockroach).