Review Article
Epidemiology, Phylogeny, and Evolution of Emerging Enteric Picobirnaviruses of Animal Origin and Their Relationship to Human Strains
Table 1
Key differences between Birnaviruses and Picobirnaviruses.
| Properties | Picobirnaviridae | Birnaviridae |
| Hosts | Mammals | Fish, chicken, and turkey | Virion size (diameter) | 35–40 nm | 65–70 nm | Capsid structure | Triangulation of 1, 3 or 4 | laevo symmetry | RNA polymerase | A-B-C motifs | C-A-B motifs | Genome size | Smaller segment—1.7 kb and larger segment—2.5 kb | Smaller segment—2.8 kb and larger segment—3.3 kb | Genome organization (open reading frames) | Two or three overlapping ORFs (segment 1) | Single ORF |
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