Global Analysis of miRNA Gene Clusters and Gene Families Reveals Dynamic and Coordinated Expression

Table 1

Enriched GO terms based on experimentally validated target mRNAs in Figure 1.

GO term	Count	𝑃 value
GO:0006355 regulation of transcription, DNA-dependent	24	5.28𝐸−26
GO:0006350 transcription	18	7.48𝐸−17
GO:0007165 signal transduction	18	2.37𝐸−14
GO:0007275 development	15	1.82𝐸−13
GO:0006508 proteolysis	14	3.32𝐸−17
GO:0045944 positive regulation of transcription from RNA polymerase II promoter	12	1.05𝐸−21
GO:0007155 cell adhesion	10	1.67𝐸−12
GO:0006915 apoptosis	10	5.62𝐸−12
GO:0008285 negative regulation of cell proliferation	9	7.05𝐸−15
GO:0006468 protein amino acid phosphorylation	9	2.03𝐸−11
GO:0006917 induction of apoptosis	8	9.59𝐸−14
GO:0042981 regulation of apoptosis	8	2.75𝐸−10

Here, we only list important GO terms that involved at least 8 target mRNAs of differentially expressed miRNAs. Count indicates involved number of target mRNAs; 𝑃 value indicates enrichment 𝑃 value.