Glucagon Effects on ³H-Histamine Uptake by the Isolated Guinea-Pig Heart during Anaphylaxis

Table 2

Obtained values of histamine, NO, O₂⁻, and H₂O₂ in the samples of coronary venous effluent collected in the absence of glucagon: before ovalbumin application, during ovalbumin application (anaphylaxis), 1 min after ovalbumin application, and 5 min after ovalbumin application.

	Histamine; (𝜇M)	NO; (nmol/mL)	O2^−; (nmol/mL)	H2O2; (nmol/mL)
Before ovalbumin application	4.8±0.42×10^−8	2.49±0.12	26.64±1.47	2.16±0.19
During ovalbumin application (anaphylaxis)	10.35^∗±0.52×10^−8	2.58±0.10	38.42^∗±1.15	3.28^∗±0.14
One minute after ovalbumin application	10.45^∗±0.51×10^−8	1.89±0.16	36.85±2.28	3.73±0.25
Five minutes after ovalbumin application	5.83±0.6×10^−8	2.92±0.42	37.44±2.4	3.94±0.45

Data are presented as mean ± SE, 𝑛=8.
*Significantly different values (𝑃<0.05).