18FDG, [18F]FLT, [18F]FAZA, and 11C-Methionine Are Suitable Tracers for the Diagnosis and In Vivo Follow-Up of the Efficacy of Chemotherapy by miniPET in Both Multidrug Resistant and Sensitive Human Gynecologic Tumor Xenografts
Figure 2
Impact of combined treatment on tumor growth. Pgp+ and Pgp− treated tumors’ volumes were compared to Pgp+ and Pgp− control (untreated) tumors in tumor-bearing animals. Treatments began 4 days after tumor cell inoculations. (a) Impact of combined treatment on A2780AD Pgp+ and A2780 Pgp− (6 mice, 24 tumors). (b) Impact of combined treatment on KB-V-1 Pgp+ and KB-3-1 Pgp− tumors (6 mice, 24 tumors). Statistically significant changes in tumor volume compared to the tumor volume of untreated control are indicated (, ).
