Neuroendocrine Differentiation Is a Prognostic Factor for Stage II Poorly Differentiated Colorectal Cancer

Table 2

Univariate analysis of clinicopathological factors for overall survival in stage II PDCRC.

Factor	𝑁		Kaplan-Meier; log rank test; 𝑃 value
	NED(−)	NED(+)
Age
<65	15	3	0.019
≥65	13	11
Gender
Male	15	3	0.391
Female	13	11
Primary tumor location
Colon	24	10	0.174
Rectum	4	4
LND
<12	8	7	0.224
≥12	20	7
Chemotherapy receipt
Yes	11	4	0.809
No	17	10
T stage
T3	15	8	0.003
T4a	10	5
T4b	3	1
Lymphatic invasion
Yes	2	2	0.469
No	26	12
NED
Positive	/	14	0.018
Negative	28	/

LND: lymph node discovered; NED: neuroendocrine differentiation.