Soluplus Graft Copolymer: Potential Novel Carrier Polymer in Electrospinning of Nanofibrous Drug Delivery Systems for Wound Therapy

Figure 5

Raman spectra of physical mixture and electrospun nanofibers of piroxicam (PRX) anhydrous form I (PRXAH I) and PCL-PVAc-PEG graft copolymer (Soluplus). (A) Pure PRXAH I; (B) physical mixture of PRXAH I and PCL-PVAc-PEG graft copolymer (Soluplus) (1 : 13 w/w); (C) PCL-PVAc-PEG graft copolymer (Soluplus) nanofibers loaded with PRXAH I in a 1 : 13 w/w drug-polymer ratio; (D) pure PCL-PVAc-PEG graft copolymer (Soluplus) nanofibers.