Potential Activity of 3-(2-Chlorophenyl)-1-phenyl-propenonein Accelerating Wound Healing in Rats
Figure 5
A histological section of a healed wound on day 10 after surgery (H&E stain, 40x magnification). Inflammatory cells (blue arrows); fibroblasts (green arrows); blood vessels (yellow arrows). (G1) The CMC group granulation tissue contains comparatively fewer fibroblasts and more inflammatory cells. (G2) The Intrasite gel group granulation tissue contains comparatively more fibroblasts and few inflammatory cells. (G3) The 25 mg/kg CPPP group granulation tissue has comparatively moderate numbers of fibroblasts and few inflammatory cells. (G4) The 50 mg/kg CPPP group granulation tissue contains comparatively more fibroblasts and few inflammatory cells. Image analysis was executed using an optical image analyzer (Image Pro plus 4.5, Media Cybernetics, Silver Spring, MD). Data was expressed as the mean ± SEM and analyzed using One Way ANOVA followed by Tukey’s post hoc test for average comparison on SPSS 18.0. Significance was defined as compared to CMC group.
