Research Article

In Vitro Chronic Administration of ERbeta Selective Ligands and Prostate Cancer Cell Growth: Hypotheses on the Selective Role of 3beta-Adiol in AR-Positive RV1 Cells

Figure 8

Relative expression of ERbeta isoforms by qPCR in Rv1 cells (a); ERbeta isoform-specific transcriptional activity induced by 3beta-Adiol and 8betaVE2 in HEK293 transfected cells ((b), (c)). ERbeta 2 and ERbeta5 were transfected separately (b) or together with ERbeta1 (c). Data are expressed as mean ± SD of the ratio between the luminescence (RLU) of the experimental over the control reporter. versus beta1 + beta5 (8betaVE2); versus the corresponding transfected cells in presence of 3beta-Adiol.
801473.fig.008a
(a) Rv1 cells
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(b) HEK293 cells
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(c) HEK293 cells