BioMed Research International / 2014 / Article / Tab 2

Research Article

BMP-4 Genetic Variants and Protein Expression Are Associated with Platinum-Based Chemotherapy Response and Prognosis in NSCLC

Table 2

The genotype frequencies for BMP-4 polymorphisms between responders and nonresponders.

RespondersNonrespondersAdjusted OR, 95% CIAdjusted
% %

5826G > A
 GG11231%18432%1
 GA17147%28349%0.99, 0.73–1.340.96
 AA8122%10719% 1.24, 0.86–1.800.25
 G39554%65157%1
 A33346%49743%1.12, 0.92–1.330.3
6007C > T
 TT7019%17931%1
 CT16746%27848%1.34, 0.98–2.110.051
 CC12735%11720%2.78, 1.91–4.03<0.001
 T30742%63655%1
 C42158%51245%1.72, 1.41–2.05<0.001

Adjusted with age, sex, smoke status, histology, stage, and chemotherapy agents.

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