Endothelium and Its Alterations in Cardiovascular Diseases: Life Style Intervention

Table 1

High endothelial venules features with respect to normal venules, modified from Miyasaka and Tanaka (2004) [12].

	Normal venules	High endothelial venules
Endothelium	Flat	Tall and plump
Basal lamina	Thin	Thick
Perivascular sheath	Scant	Prominent
PECAM-1	Moderate	Moderate
ICAM-1	Very weak/absent	High
VE-cadherin	Moderate	Moderate

PECAM-1: platelet/endothelial cell adhesion molecule-1; ICAM-1: intercellular adhesion molecule-1; VE-cadherin: vascular endothelial-cadherin.