Clonotypic Analysis of Immunoglobulin Heavy Chain Sequences in Patients with Waldenström’s Macroglobulinemia: Correlation with MYD88 L265P Somatic Mutation Status, Clinical Features, and Outcome

Table 3

Mean (median) of somatic mutations’ percentage in different groups.

	Mean (median) somatic mutations’ percentage	Range (%)
In all 35* cases	7,5% (7,3%)	0–16,1
In 32 cases with mutated genes (<98% homology)	8,1% (7,6%)	2,83–16,1
In IGHV3 cases’ group (27 cases)	8% (8,3%)	0–14,46
In IGHV3-23 cases’ group (9 cases)	9,4% (9,7%)	2,83–14,46
In IGHV3-74 cases’ group (6 cases)	7,5% (8,1%)	4,02–9,65

*34 patients, 1 with two clones; IGHV3-74 and IGHV4-59.