Curcumin, a Natural Antioxidant, Acts as a Noncompetitive Inhibitor of Human RNase L in Presence of Its Cofactor 2-5A In Vitro

Table 1

Results of the molecular docking experiment (number of poses having binding energy).

S. number	Between −4 and −5 kcal/mol	Between −5 and −6 kcal/mol	Between −6 and −7 kcal/mol	Between −7 and −8 kcal/mol	Greater than −8 kcal/mol
Site 1	8	22	114	6	0
Site 2	0	87	49	14	0
Site 3	5	78	67	0	0
Site 4	0	0	29	103	18
Site 5	0	89	61	0	0

Clustering of highest number of poses with binding energy greater than −7 kcal/mol occurs mostly at sites 4 and 2, respectively.