Table 3: Additional surgery according to FS and final histopathology at margins of surgical specimens.

Clinical outcomesFS(%) Borderline malignancies recognized by FS(%) Additional Surgery according to FS(%)Final histopathological diagnoses at surgical margin
SCC(%)CIS(%)Epithelial dysplasiaNormal(%)
Moderate(%)Mild(%)

Relapse-free ( )Yes128(67.0) Yes 55(43.0)Yes38(69.1)2(5.3)6(15.8)12(31.6)18(47.3)0(0.0)
No17(30.9)0(0.0)3(17.6)8(47.1)5(29.4)1(5.9)
No73(57.0)1(1.4)1(1.4)11(15.0)57(78.1)3(4.1)
No63(33.0)0(0.0)8(12.7)33(52.4)22(34.9)0(0.0)

Relapse ( )yes83(54.6) Yes 57(68.7)Yes39(68.4)6(15.4)17(43.6)13(33.3)3(7.7)0(0.0)
No18(31.6)3(16.7)9(50.0)6(33.3)0(0.0)0(0.0)
No26(31.3)4(15.4)6(23.1)8(30.8)7(26.9)1(3.8)
No69(45.4)10(14.5)32(46.4)13(18.8)13(18.8)1(1.5)