Overexpression of Wnt5a Promotes Angiogenesis in NSCLC

Table 1

Correlation between Wnt5a and clinicopathological features in NSCLC.

Variant	Total	Wnt5a		𝑥^2	P value
	𝑛	Negative (%)	Positive (%)
Gender
Male	145	47 (32.41)	98 (67.59)	6.674	0.012
Female	60	31 (51.67)	29 (48.33)
Age (yr)
<60	101	37 (36.63)	64 (63.37)	0.169	0.774
≥60	104	41 (39.42)	63 (60.58)
Size (cm)
<3	29	11 (37.93)	18 (62.07)	0.000	1.000
≥3	176	67 (38.07)	109 (61.93)
Location
Center	106	38 (35.85)	68 (64.15)	0.451	0.565
Peripheral	99	40 (40.40)	59 (59.60)
Histological classification
SCC	79	23 (29.11)	56 (70.89)	8.222	0.016
AC	75	38 (50.67)	37 (49.33)
LCC	51	17 (33.33)	34 (66.67)
Differentiation
Well	35	17 (48.57)	18 (51.43)	2.044	0.360
Moderate	87	32 (36.78)	55 (63.22)
Poor	83	29 (34.94)	54 (65.06)
Pleura invasion
No	113	39 (34.51)	74 (65.49)	1.335	0.252
Yes	92	39 (42.39)	53 (57.61)
Lymph node metastasis
No	117	45 (38.46)	72 (61.54)	0.020	1.000
Yes	88	33 (37.50)	55 (62.50)
T stage
T1 + T2	149	56 (37.58)	93 (62.42)	0.050	0.872
T3 + T4	56	22 (39.29)	34 (60.71)
Clinical stage
I + II	158	62 (39.24)	96 (60.76)	0.415	0.609
III + IV	47	16 (34.04)	31 (65.96)
Distant metastasis
No	147	57 (38.78)	90 (61.22)	0.116	0.752
Yes	58	21 (36.21)	37 (63.79)
Therapy before surgery
No	186	69 (37.10)	117 (62.90)	0.772	0.458
Yes	19	9 (47.37)	10 (52.63)

𝑃<0.05 means statistical significance.