Table 2: Top three most enriched biological processes of genes differentially expressed in human peripheral blood mononuclear cells when exposed to varying doses of 60Co radiation according to the gene ontology enrichment analysis.

DoseGO IDBiological process value (BH) Gene symbol

0.5GO:0045935 Positive regulation of nucleobase-containing compound metabolic process 0.0012aSS18, SMARC2, EPAS1, LHX1, ZNF148, KLF6, F2R
GO:0051254 Positive regulation of RNA metabolic process 0.0006aTNSF10, MCL1
GO:2001236 Regulation of extrinsic apoptotic signaling pathway 0.0011aTNSF10, MCL1

1GO:0002376Immune system process0.0018 109 genesb
GO:0006955Immune response0.0213 69 genesb
GO:0012501Programmed cell death0.03 88 genesb

2.5GO:0044092 Negative regulation of molecular function 0.0299 NKX3-1, DUSP6, CDC27, PRDX3, CAST, PSMC2, BAX, AZIN1, PSMA1, PELI1, CD44, HIPK3, SERPINB2, PI3, SENP2, RLIM, THBS1
GO:0019221 Cytokine-mediated signaling pathway 0.0299 IL1R1, RANBP2, CCL2, NUP54, CD44, IL1A, IFNGR1, KLF6, EIF4G2, JAK3, CXCR3, HLA-DRB5
GO:0071345 Cellular response to cytokine stimulus 0.0299 RANBP2, IL1R1, RANBP2, CCL2, NUP54, CD44, IL1A, IFNGR1, KLF6, EIF4G2, JAK3, CXCR3, HLA-DRB5

5GO:0071310 Cellular response to organic substance 0.009 34 genesb
GO:0019221 Cytokine-mediated signaling pathway 0.0034 USP18, NUP54, IFNAR1, IL1A, CXCR3, EIF4G2, NUP98, TRADD, SOCS3, NUMBL, RANBP2, PML, PTPRN, CD44, JAK3, HLA-DRB5, CAMK2A
GO:0070887 Cellular response to cytokine stimulus 0.016237 genesb

The raw value for the GO analysis.
The gene identities are given in the Supplementary Material 1 along with the rest of the GO enrichment analysis results.