The Effects of Spinal, Inhalation, and Total Intravenous Anesthetic Techniques on Ischemia-Reperfusion Injury in Arthroscopic Knee Surgery

Table 2

Changes in plasma MDA levels.

	𝑡1	𝑡2	𝑡3	𝑡4	𝑡5	𝑡6	𝑡7	𝑡8	𝑡9
Group S	1.8±0.13	3.1±0.14	3.27±0.19	2.9±0.15	3.5±0.17	3.25±0.16	3.25±0.16	3.52±0.17	3.46±0.13
Group I	1.74±0.07	1.92±0.11	1.68±0.09	1.73±0.07	1.91±0.14	2.37±0.14	1.9±0.13	1.83±0.08	2.24±0.17
Group T	1.79±0.06	2.23±0.20	1.59±0.05	1.55±0.06	1.65±0.05	1.99±0.07	2.15±0.09	2.21±0.14	2.43±0.13
𝑃	0.250	0.009^a,b	<0.0005^a,b	<0.0005^a,b	<0.0005^a,b	0.008^a,b	0.004^a,b	0.001^a,b	0.018^a

Plasma levels of malonyldialdehyde (MDA) (mmol/L). From all patients, preoperatively (𝑡₁), 30 min after tourniquet inflation (𝑡₂), immediately before (𝑡₃), and 5 min (𝑡₄), 15 min (𝑡₅), 30 min (𝑡₆), 1 h (𝑡₇), 2 h (𝑡₈), and 6 hours (𝑡₉) after tourniquet release. (𝑃<0.05; for a: Group T versus S, for b: Group I versus S). Group I: inhalation, Group S: spinal, and Group T: total intravenous anesthesia group.